Gestational exposure to environmental chemical mixtures and cognitive abilities in children: A pooled analysis of two North American birth cohorts.

ABSTRACT:

Background

Gestational exposures to single toxic chemicals have been associated with cognitive deficits in children, but few studies have explored chemical mixtures.

Objectives

To evaluate the associations between gestational chemical biomarker mixtures and cognitive abilities in children from two prospective cohorts.

Methods

This study includes 617 birthing parent-child pairs from the Health Outcomes and Measures of the Environment (HOME) and Maternal-Infant Research on Environmental Chemicals (MIREC) Studies. We measured 29 chemical biomarkers (metals, persistent organic pollutants, perfluoroalkyl substances, organophosphate esters, phenols, phthalates, organophosphate pesticides, and parabens) in pregnant individuals during early pregnancy and their children's cogn

SUBMITTER: Puvvula J 

PROVIDER: S-EPMC11896093 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature