Quantitative Analysis of Small Intestinal Motility in 3D Cine-MRI Using Centerline-Aware Motion Estimation.

ABSTRACT:

Background

Currently available tools for noninvasive motility quantification of the small intestine are limited to dynamic 2D MRI scans, which are limited in their ability to differentiate between types of intestinal motility.

Purpose

To develop a method for quantification and characterization of small intestinal motility in 3D, capable of differentiating motile, non-motile and peristaltic motion patterns.

Study type

Prospective.

Subjects

Fourteen healthy volunteers (127 small intestinal segments) and 10 patients with Crohn's disease (87 small intestinal segments).

Field strength/sequence

3.0 T, 3D balanced fast field echo sequence, 1 volume per second.

Assessment

Using deformable image registration between subsequent volumes, the local velocity w

SUBMITTER: van Harten LD 

PROVIDER: S-EPMC11896920 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature