Associations Between Brain Metabolites Measured With MR Spectroscopy and Head Impacts in High School American Football Athletes.

ABSTRACT:

Background

While changes in brain metabolites after injury have been reported, relationships between metabolite changes and head impacts are less characterized.

Purpose

To investigate alterations in neurochemistry in high school athletes as a function of head impacts, concussion, and the use of a jugular vein compression (JVC) collar.

Study type

Prospective controlled trial.

Subjects

A total of 284 male American football players, divided into JVC collar and noncollar groups; 215 included in final analysis (age = 15.9 ± 1.0 years; 114 in collar group).

Field strength/sequence

3 Tesla/T₁-weighted gradient echo, ¹H point resolved spectroscopy, acquired between August and November 2018.

Assessment

Head impacts were quantified usi

SUBMITTER: Liu Z 

PROVIDER: S-EPMC11896922 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature