Complementary classification of hypertrophic cardiomyopathy using unsupervised cluster analysis on left ventricular function.

ABSTRACT: Contemporary classification of hypertrophic cardiomyopathy (HCM) was mainly based on the site of myocardial hypertrophy and left ventricular outflow tract obstruction. A complementary classification based on left ventricular function could provide a powerful tool to identify individuals with high risk of adverse cardiovascular outcomes and guide individualized managements. Multi-dimensional echocardiographic parameters of left ventricular function derived from conventional echocardiography, tissue Doppler imaging, and speckle tracking echocardiography were obtained in 266 HCM patients and 169 healthy controls (HCs). According to these parameters, HCM subtypes were calculated by principal component analysis and unsupervised cluster analysis. Variables of different groups were compared. The

SUBMITTER: Sun D 

PROVIDER: S-EPMC11897254 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature