Highly Elastic, Biodegradable Polyester-Based Citrate Rubber for 3D Printing in Regenerative Engineering.

ABSTRACT: Highly elastic and 3D-printable degradable elastomers are advantageous for many biomedical applications. Herein, we report the synthesis of a biodegradable citrate rubber poly(tetrahydrofuran-co-citrate-co-hydroxyl telechelic natural rubber) (PTCR) using citric acid, poly(tetrahydrofuran), and hydroxyl telechelic natural rubber. The citrate rubber PTCR is methacrylated to synthesize a prepolymer methacrylated-PTCR (mPTCR) that can be used to fabricate bioresorbable scaffolds via 3D printing using micro-continuous liquid interface production. Polymers were chemically characterized via NMR spectroscopy, FTIR spectroscopy, DSC, and TGA and mechanically characterized via tensile testing and crimping. The addition of rubber improved the elasticity of PTCR (658 ± 68% for dry and 41

SUBMITTER: Khan A 

PROVIDER: S-EPMC11897938 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature