Loss of Pleiotropic Regulatory Functions in <i>Tannin1</i>, the Sorghum Ortholog of Arabidopsis Master Regulator <i>TTG1</i>.

ABSTRACT: Transcriptional master regulators are often targeted to improve plant traits, but antagonistic pleiotropic effects of these regulators can hamper this approach. The Myb-bHLH-WDR (MBW) complex is a broadly conserved transcriptional regulator affecting pigmentation, biotic stress resistance, and abiotic stress tolerance. We investigated the function of sorghum grain pigmentation regulator Tannin1, the ortholog of Arabidopsis pleiotropic WD40 regulator TTG1, to test for conserved pleiotropic regulatory effects and to better understand the evolution of the MBW complex in Poaceae. We characterized genome-wide differential expression of leaf tissue using RNA sequencing in near-isogenic lines (NILs) that contrasted wildtype Tan1 and loss-of-function tan1-b alleles, und

SUBMITTER: Schuh A 

PROVIDER: S-EPMC11898007 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature