Serum Lactate Dehydrogenase Levels Reflect the Lung Injury Extension in COVID-19 Patients at Hospital Admission.

ABSTRACT:

Background

Several hematological and biochemical parameters have been related to the COVID-19 infection severity and outcomes. However, less is known about clinical indicators reflecting lung involvement of COVID-19 patients at hospital admission. Computed tomography (CT) represents an established imaging tool for the detection of lung injury, and the quantitative analysis software CALIPER has been used to assess lung involvement in COVID-19 patients. Herein, the relationship between the lung involvement expressed by CALIPER interstitial lung disease (ILD) percentage and a set of blood parameters related to tissue oxygenation and damage in COVID-19 patients at hospital admission was evaluated.

Methods

We performed a retrospective and a prospective study involving 321 and 75,

SUBMITTER: Bertilacchi MS 

PROVIDER: S-EPMC11898011 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature