Is Childhood IgA Nephropathy Different From Adult IgA Nephropathy? A Narrative Review.

ABSTRACT:

Purpose of the review

Immunoglobulin A (IgA) nephropathy (IgAN) is the most common primary glomerular kidney disease. Children and adults are presumed to have the same disease and are treated similarly. However, there are differences between childhood IgAN and adult IgAN that may require unique treatment considerations, even after transition to adult nephrology services. A narrative review was conducted to compare childhood and adult IgAN and to describe the distinct characteristics of childhood IgAN. Reframing childhood IgAN can inform guideline recommendations unique to childhood IgAN, the development of targeted therapies, and clinical trial design.

Sources of information

Medline and Embase were searched for reports on children and adults with IgAN published between Janua

SUBMITTER: Alladin-Karan A 

PROVIDER: S-EPMC11898040 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature