Elevated Fracture Risks in Patients Using Inhaled Corticosteroids: A Korean Nationwide Study.

ABSTRACT:

Backgruound

In this comprehensive retrospective nationwide cohort study, we examined the relationships between various asthma medications and bone health, utilizing data from the National Health Insurance Service database of South Korea.

Methods

From 2015 to 2019, the relevant dataset included 168,611 individuals aged 66 years, among whom 8,747 were diagnosed with asthma. We focused on a subset of 6,173 patients, all 66-year-old women. Participants were categorized into four groups: nonusers of asthma medication (n=2,868), leukotriene antagonist users (n=2,281), inhaled corticosteroid (ICS) users (n=517), and those using a combination of ICS and long-acting beta-agonist (ICS+LABA) medication (n=507). The primary outcomes measured were the incidences of major osteoporotic fra

SUBMITTER: Kong SH 

PROVIDER: S-EPMC11898311 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature