Triiodothyronine Is Associated with Incidence/Resolution of Steatotic Liver Disease: Longitudinal Study in Euthyroid Korean.

ABSTRACT:

Backgruound

The positive relationship between triiodothyronine (T3) and steatotic liver disease (SLD) demonstrated only in crosssectional study. We aimed to evaluated whether total T3 (TT3) is associated with the development/resolution of SLD in longitudinal design.

Methods

This retrospective, longitudinal, population-based cohort study included 1,665 South Korean euthyroid adults with ≥4 thyroid function test. We explored the impact of mean TT3 during follow-up on development/resolution of either SLD (diagnosed by ultrasound) or modified metabolic dysfunction-associated steatotic liver disease (MASLD) using Cox proportional hazards regression models.

Results

During about median 5 years follow-up, 807/1,216 (66.3%) participants among participants without SLD at baseli

SUBMITTER: Kim HI 

PROVIDER: S-EPMC11898316 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature