Comparison of the diagnostic accuracy between ¹⁸F-FAPI-04 PET/CT and ¹⁸F-FDG PET/CT in the clinical stage IA of lung adenocarcinoma.

ABSTRACT:

Background

Fluorine 18-labeled fibroblast activation protein inhibitor (¹⁸F-FAPI-04) positron emission tomography/computed tomography (PET/CT) has shown promise for the visualization of advanced stage lung cancer. The accuracy of ¹⁸F-FAPI-04 compared with that of fluorine-18 labeled-fluorodeoxyglucose (¹⁸F-FDG) in detecting early lung adenocarcinoma (LUAD) remains unknown. Taking the surgical pathology of pulmonary nodule as the gold standard, the diagnostic performance of stage IA LUAD were compared between ¹⁸F-FAPI-04 PET/CT and ¹⁸F-FDG PET/CT, and the correlation between ¹⁸F-FAPI-04 uptake and pathological characteristics of stage IA LUAD.

Methods

This prospective study from February 2023 to October 2023 an

SUBMITTER: Liang HX 

PROVIDER: S-EPMC11898335 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature