Survival advantage of radiotherapy and nomogram for patients with pulmonary neuroendocrine neoplasms: a propensity score-matched Surveillance, Epidemiology, and End Results database study.

ABSTRACT:

Background

The standard treatment for pulmonary neuroendocrine neoplasms (pNENs) is surgery in the early stage and is generally determined according to the histologic type and stage. Radiotherapy (RT) is a treatment option for locally advanced or unresectable lung cancers. The aim of this study was to determine the prognostic value of RT in patients with pNENs using data from the Surveillance, Epidemiology, and End Results database.

Methods

We used propensity score matching analysis to balance differences in variables between the RT and no-RT groups. Univariate and multivariate Cox proportional hazards regression analyses were used to evaluate the factors related to overall survival and cancer-specific survival (CSS). A novel nomogram was constructed, and the results were ev

SUBMITTER: Tong J 

PROVIDER: S-EPMC11898353 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature