Inter-Software Reproducibility of Quantitative Values of Myocardial Blood Flow and Coronary Flow Reserve Acquired by [¹³N]NH₃ MPI PET/CT and the Effect of Motion Correction Tools.

ABSTRACT: Background: The choice of software package (SP) for image processing affects the reproducibility of myocardial blood flow (MBF) values in [¹³N]NH₃ PET/CT scans. However, the impact of motion correction (MC) tools-integrated software motion correction (ISMC) or data-driven motion correction (DDMC)-on the inter-software reproducibility of MBF has not been studied. This research aims to evaluate reproducibility among three commonly used SPs and the role of MC. Methods: Thirty-six PET/CT studies from patients without myocardial ischemia or infarction were processed using QPET, Corridor-4DM (4DM), and syngo.MBF (syngo). MBF and coronary flow reserve (CFR) values were obtained without motion correction (NMC) and with ISMC and DDMC. Intraclass correlation coeff

SUBMITTER: Mendoza-Ibanez OI 

PROVIDER: S-EPMC11898590 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature