Dehydration-induced <i>Ae-Aper50</i> regulates midgut infection in <i>Aedes aegypti</i> mosquitoes.

ABSTRACT: Climate change is predicted to increase the spread of mosquito-borne viruses, but genetic mechanisms underlying the influence of environmental variation on the ability of insect vectors to transmit human pathogens is unknown. In response to a changing climate, mosquitoes will experience longer periods of drought. An important physiological response to dry environments is the protection against dehydration, here defined as desiccation tolerance. While temperature is known to impact interactions between mosquito and virus, the role of dehydration remains unknown. We identified two genetically diverse lines of the mosquito Aedes aegypti, a major arbovirus vector, with marked differences in desiccation tolerance. To determine the genetic response to dehydration between these contrasting

SUBMITTER: Accoti A 

PROVIDER: S-EPMC11898677 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature