Large diversity in the O-chain biosynthetic cluster within populations of Pelagibacterales.

ABSTRACT: Genomic diversity in prokaryotic species is largely due to the existence of extensive pangenomes, allowing different gene complements to be drawn depending on the strain. Here, we have studied the diversity of the O-chain polysaccharide biosynthesis cluster (OBC) in marine bacteria of the Pelagibacterales order as a proxy to measure such genetic diversity in a single population. The study of single-amplified genomes (SAGs) from the whole order found a pattern similar to that of other well-studied microbes, such as the Enterobacteriales or Alteromonas, where distinct OBCs represent strains containing different gene pools. We found that most of the OBC sharing happened among individuals of the same clonal frame (>99% average nucleotide identity). Moreover, given the parsimonious way t

SUBMITTER: Haro-Moreno JM 

PROVIDER: S-EPMC11898729 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature