A retrospective cohort study on radio/chemotherapy and survival following esophageal fistula in esophageal cancer patients with prior radiotherapy.

ABSTRACT:

Background/objective

Radiotherapy is a common treatment for patients with esophageal cancer. Esophageal fistula (perforation) is a serious complication in patients with advanced esophageal cancer. It is unclear how radio/chemotherapy post-fistula may affect survival in patients with malignant esophageal fistulae with radiotherapy pre-fistula. We sought to evaluate radio/chemotherapy and survival post-fistula in patients with esophageal cancer and radiotherapy pre-fistula.

Methods

In a retrospective cohort study, we reviewed post-fistula treatments and survival in 98 patients with esophageal cancer and prior radiotherapy with or without chemotherapy between 2010/6 and 2023/5 in a regional cancer care centre in Zhengzhou, China. The primary outcome was survival time (months) p

SUBMITTER: Xu W 

PROVIDER: S-EPMC11899130 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature