Cumulative blood pressure predicts risk of cardiovascular outcomes in middle-aged and older population.

ABSTRACT:

Background

Cardiovascular disease (CVD) remains a major health concern globally, contributing to a considerable disease burden. However, few studies have considered long-term cumulative blood pressure (cBP) exposure in middle-aged and older population in China. The aim of this study was to investigate whether long-term cBP was associated with subsequent cardiovascular outcomes among participants without CVD at baseline in Chinese over 45 years old.

Methods

6435 participants in China of the CHARLS (The China Health and Retirement Longitudinal Study) were included. Cumulative BP was calculated as the area under the curve using measurements from wave 1 (2011) to wave 2 (2013). Outcomes included CVD, heart disease and stroke.

Results

During a median follow-up period of 5 

SUBMITTER: You FF 

PROVIDER: S-EPMC11899200 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature