Unveiling microRNA-like small RNAs implicated in the initial infection of <i>Fusarium oxysporum</i> f. sp. <i>cubense</i> through small RNA sequencing.

ABSTRACT: Banana Fusarium wilt (BFW), caused by Fusarium oxysporum f. sp. cubense (Foc), poses a major challenge to the worldwide banana industry. Fungal microRNA-like small RNAs (milRNAs) play crucial roles in regulating fungal growth, conidiation, development, and pathogenicity. However, the milRNAs and their functions in the pathogenesis of Foc remain poorly understood. In this study, we employed high-throughput sequencing and bioinformatics to profile Foc sRNAs during both pure culture and early infection stages. Our analysis identified six milRNAs exhibiting significantly upregulated expression at the initial Foc infection. Of these, milR106's biogenesis was found to be Dicer-dependent, whereas milR87, milR133, milR138, and milR148 were associated with

SUBMITTER: Xie L 

PROVIDER: S-EPMC11899247 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature