Advances in gut microbiota-related treatment strategies for managing colorectal cancer in humans.

ABSTRACT: Colorectal cancer (CRC) is a major contributor to global cancer-related mortality with increasing incidence rates in both developed and developing regions. Therefore, CRC presents a significant challenge to global health. The development of innovative tools for enhancing early CRC screening and diagnosis, along with novel treatments and therapies for improved management, remains an urgent necessity. CRC is intricately associated with the gut microbiota, which is integral to food digestion, nutrient generation, drug metabolism, metabolite production, immune enhancement, endocrine regulation, neurogenesis modulation, and the maintenance of physiologic and psychological equilibrium. Dysbiosis or imbalances in the gut microbiome have been implicated in various disorders, including CRC. Emergin

SUBMITTER: Roy B 

PROVIDER: S-EPMC11899591 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature