Clinicopathological features of early-onset colorectal cancer in Japanese patients: a single-center retrospective study.

ABSTRACT:

Background

The incidence of early-onset colorectal cancer (EoCRC), defined as CRC diagnosed at < 50 years of age, is increasing globally. However, only a few studies are reported from Japan, and the clinicopathological features of EoCRC in Japanese patients remain unknown.

Methods

We retrospectively investigated consecutive Japanese patients who were pathologically diagnosed with invasive CRC at our hospital from January 2015 to December 2021. Patients were categorized into those who were diagnosed with CRC at < 50 years (early-onset group) and ≥ 50 years (late-onset group) of age. We compared the clinicopathological findings between the two groups.

Results

The analysis included 731 patients. EoCRC was diagnosed in 46 patients　(6.3% of all patients). Of them, 41.3% de

SUBMITTER: Okagawa Y 

PROVIDER: S-EPMC11899674 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature