Structural Cerebellar and Lateral Frontoparietal Networks are altered in CUD: An SBM Analysis.

ABSTRACT: Repetitive drug use results in enduring structural and functional changes in the brain. Addiction research has consistently revealed significant modifications in key brain networks related to reward, habit, salience, executive function, memory and self-regulation. Techniques like Voxel-based Morphometry have highlighted large-scale structural differences in grey matter across distinct groups. Source-based Morphometry (SBM) takes this a step further by incorporating the Independent Component Analysis to detect shared patterns of grey matter variation, all without requiring prior selection of regions of interest. However, SBM has yet to be employed in the study of structural alteration patterns related to cocaine addiction. Therefore, we performed this analysis to explore alterations in stru

SUBMITTER: Lacomba-Arnau E 

PROVIDER: S-EPMC11899759 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature