Whether preoperative biliary drainage leads to better patient outcomes of pancreaticoduodenectomy: a meta-analysis and systematic review.

ABSTRACT:

Objective

To investigate whether preoperative biliary drainage is beneficial for patients undergoing pancreaticoduodenectomy.

Methods

The PubMed, Cochrane Library and the Web of Science were systematically searched for relevant trials that included outcome of pancreaticoduodenectomy with and without preoperative biliary drainage from January 2010 to May 2024. The primary outcomes are postoperative pancreatic fistula and intra-abdominal infection. Data is pooled using the risk ratio or standardized mean difference with 95% confidence interval. The study protocol was registered prospectively with PROSPERO (CRD42022372584).

Results

A total of 39 retrospective cohort studies with 33,516 patients were included in this trial. Compared with no preoperative biliary drainage,

SUBMITTER: Zhang B 

PROVIDER: S-EPMC11900024 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature