Synthesis, Physicochemical Properties and Anti-Fungal Activities of New <i>Meso</i>-Arylporphyrins.

ABSTRACT: In this work, we describe the synthesis of three new meso-arylporphyrins, named meso-tetrakis [4-(nicotinoyloxy)phenyl] porphyrin (H₂TNPP), meso-tetrakis [4-(picolinoyloxy)phenyl] porphyrin (H₂TPPP), and meso-tetrakis [4-(isonicotinoyloxy) phenyl] porphyrin (H₂TIPP). These new synthesized meso-arylporphyrins are characterized using spectroscopic analysis: Fourier Transform Infrared Spectroscopy (FTIR) and One-dimensional Nuclear Magnetic Resonance (1D NMR), and mass spectrometry (MS). The photophysical studies (UV-visible absorption, singlet oxygen (¹O₂) luminescence, and fluorescence emissions) demonstrate their potential uses as photosensitizers (PSs) in photodynamic therapy (PD

SUBMITTER: Mkacher H 

PROVIDER: S-EPMC11900167 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature