Non-linear association between interpregnancy interval after vaginal delivery and singleton preterm birth: a retrospective cohort study.

ABSTRACT:

Background

The association between interpregnancy interval (IPI) after vaginal delivery and preterm birth (PTB) in singleton has not been elucidated. The aim of this study is to investigate the association between interpregnancy interval after vaginal delivery and preterm birth.

Methods

Birth data from the 2022 National Vital Statistics System (NVSS) were selected, and multinomial logistic regression models were used to determine the odds ratios (OR) and 95% confidence intervals (95% CI) for the association between IPI after vaginal delivery and PTB. A restricted cubic spline (RCS) model with multivariate adjustment was constructed with a 4-node OR curve to check for possible non-linear relationships. Threshold effect analysis was conducted using two-piecewise linear regress

SUBMITTER: Zhuang T 

PROVIDER: S-EPMC11900573 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature