A standard gamble study to determine health state utilities associated with seizures in glioma in the UK.

ABSTRACT:

Background

Glioma are infiltrative primary brain tumours, which despite treatment, lead to a substantial reduction in life expectancy. Seizures are a common symptom of glioma, and have a serious impact on patient health related quality of life (HRQoL).

Objective

The study aimed to estimate health state utility values for different types of seizures related to glioma, a serious type of brain tumour.

Methods

Vignettes for the different health states were initially developed from the existing literature. The health states were then refined in collaboration with patients with previous experience of seizures and clinicians experienced in treating patients with seizures. The final vignettes represented three types of acute seizure: focal aware, focal impaired awareness and

SUBMITTER: Robinson T 

PROVIDER: S-EPMC11900579 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature