Efficacy of Myopia Prevention in At-Risk Children: A Systematic Review and Network Meta-Analysis.

ABSTRACT: Objectives: To evaluate the efficacy of myopia prevention methods in children without pre-existing myopia. Methods: A network meta-analysis was conducted following the PRISMA-NMA guidelines. Comprehensive searches were performed in PubMed, Embase, and Cochrane CENTRAL databases. The analysis focused on randomized controlled trials evaluating myopia prevention strategies in children without prior myopia. Primary outcomes included annual changes in refraction and axial length, while secondary outcomes encompassed myopia incidence and adverse events. Effect sizes were reported as risk ratios (RR) or mean differences (MD) with 95% confidence intervals (CIs). Data synthesis utilized a random-effects model under a frequentist framework, with intervention efficacy ranked by P-scores

SUBMITTER: Lee SH 

PROVIDER: S-EPMC11900620 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature