Bioactives derived from Brazilian native flora with antimicrobial and anticancer activity.

ABSTRACT:

Background

The development of new drugs that act against multidrug-resistant microorganisms and malignant tumors is necessary owing to the limited therapeutic options and high mortality rates associated with these pathologies. In this study, we evaluated the phytochemical groups present in seven plants from the Brazilian Cerrado even as their antioxidant, antiproliferative and antimicrobial activities.

Methods

The extracts were obtained by the maceration technique and secondary metabolites were determined by phytochemical analysis. The antioxidant activity was assessed by the DPPH (2,2-diphenyl-1-picrylhydrazyl) free radical scavenging method. The antiproliferative activity of the extracts was assessed using human breast, kidney, and liver neoplastic cells. Cytotoxicity was

SUBMITTER: Vitorelli-Venancio DC 

PROVIDER: S-EPMC11900633 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature