Associations between multiple inflammatory biomarkers and the risk of developing kidney stones.

ABSTRACT:

Objectives

Nephrolithiasis, with a prevalence of 9% and increasing worldwide, has a recurrence rate close to 50%. Urinary stones significantly impact quality of life and impose substantial economic burdens on patients and healthcare systems. Systemic inflammation is postulated as a risk factor for urinary stones. Previous studies have identified associations between inflammatory markers and kidney stones, but these often rely on patient recall, introducing potential recall bias. This study investigates whether inflammatory markers vary according to the presence of nephrolithiasis using health check-up data from a large cohort in South Korea.

Materials and methods

Data were collected from participants in health checkups at a university hospital in Seoul between 2010 and 2020.

SUBMITTER: Lee JH 

PROVIDER: S-EPMC11900638 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature