Triple-Negative Breast Cancer in Older Patients: Does SLNB Guide Therapy?

ABSTRACT:

Background

Older breast cancer patients represent a heterogeneous population. Studies demonstrate that sentinel lymph node biopsy (SLNB) omission may be appropriate in some clinical scenarios, yet patients with triple-negative breast cancer (TNBC) are often excluded from these studies. This study evaluated differences in treatment and survival for older patients with TNBC based on SLNB receipt and result.

Methods

Patients 70 years old or older with a diagnosis of cT1-2/cN0/M0 TNBC (2010-2019) who underwent surgery were selected from the National Cancer Database. Logistic regression estimated the association of SLNB with therapy, and Cox proportional hazards models estimated the association of SLNB with overall survival (OS) after adjustment for select factors.

Results

SUBMITTER: Record SM 

PROVIDER: S-EPMC11900900 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature