Acquired Hemophilia-A Case Series and Review.

ABSTRACT: Background: Acquired hemophilia A (AHA) is a rare, life-threatening autoimmune disorder characterized by inhibitory autoantibodies against factor VIII (FVIII), resulting in spontaneous or trauma-related bleeding. This study reviews a single-center cohort to evaluate patient characteristics, treatments, and outcomes. Methods: We retrospectively reviewed the records of 22 adult patients diagnosed with AHA between 2012 and 2024. The data included demographics, clinical presentation, laboratory findings, treatments, and outcomes. Statistical analysis compared genders and evaluated treatment strategies and remission outcomes. Results: The cohort had an equal gender distribution with an average age of 62 years (22-102 years). Suspected etiologies included pregnancy (27%), ma

SUBMITTER: Waldman Radinsky L 

PROVIDER: S-EPMC11901076 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature