Breastfeeding Shapes the Gut Microbiota and Its Structure Is Associated with Weight Gain Trajectories in Mexican Infants.

ABSTRACT: Background: Rapid weight gain in early infancy increases the risk of childhood obesity, while exclusive breastfeeding can protect against it, depending on breastmilk composition, maternal diet, and infant gut microbiota. Objective: The objective of this study was to analyze the association between maternal diet, breastmilk components, infant gut microbiota, and weight gain in the first year of life of Mexican breastfed infants. Methods: This longitudinal study included 27 mothers with exclusively breastfed infants (≥5 months of age). We evaluated maternal diet and breastmilk composition at 5 months postpartum (pp), the infant fecal microbiota at 5 and 12 months pp using 16S rRNA gene sequencing, and weight gain as normal, rapid or slow weight gain (NWG, RWG or SWG) in

SUBMITTER: Arguelles-Lopez A 

PROVIDER: S-EPMC11901506 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature