Solvent Fractionation and LC-MS Profiling, Antioxidant Properties, and α-Glucosidase Inhibitory Activity of <i>Bombyx batryticatus</i>.

ABSTRACT: Bombyx batryticatus is the dried body of silkworm (Bombyx mori Linnaeus) larvae infected with Beauveria bassiana. It is widely used in traditional Chinese medicine for treating convulsions, epilepsy, and hyperglycemia. In this study, Bombyx batryticatus and its extract were prepared. The total reducing power, hydroxyl radical scavenging and superoxide anion radical scavenging activities, as well as the α-glucosidase inhibitory activity of Bombyx batryticatus extract were superior to those of normal silkworm larvae extract. Among them, the IC₅₀ value of Bombyx batryticatus extract for α-glucosidase was 5.76 mg/mL, while that of normal silkworm larvae extract was 7.0 mg/mL. Untargeted metabolomic analysis was employed to compare the materi

SUBMITTER: Liu G 

PROVIDER: S-EPMC11901607 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature