Chemical Analysis and Antioxidant Activities of Resin Fractions from <i>Pistacia lentiscus</i> L. <i>var. Chia</i> in Neuroblastoma SH-SY5Y Cells.

ABSTRACT: Chios mastiha is the natural aromatic resin of Pistacia lentiscus L. var. Chia, Anacardiaceae, which is exclusively cultivated in the southern part of the Greek island of Chios. Chios mastiha (P. lenticonus/Chios mastiha) is well-known for its distinctive taste and aroma and has been known since ancient times due to its healing properties in gastrointestinal and inflammatory disorders and because of its anti-bacterial and anti-fungal activities. In this study, the chemical composition, applying LC-QTOF-MS/MS analysis, and the antioxidant activities of three different polarity P. lenticonus/Chios mastiha fractions, apolar, medium polar, and polar, were characterized in human neuroblastoma SH-SY5Y cells. Chemical analysis of the fractions unveiled new compo

SUBMITTER: Georgantopoulos A 

PROVIDER: S-EPMC11901618 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature