Aqueous <i>Cymbopogon citratus</i> Extract Mediated Silver Nanoparticles: Part I. Influence of Synthesis Parameters, Characterization, and Biomedical Studies.

ABSTRACT: This study explores the green synthesis of silver nanoparticles (AgNPs) using Cymbopogon citratus (lemongrass) extract as a reducing agent. Synthesis was confirmed by a color change (light yellow to dark brown) under optimal conditions: 1.50 mM silver nitrate, 3.5% v/v extract, at 100 °C, with a pH of 9, and for 60 min. The AgNPs exhibited spherical morphology, a hydrodynamic diameter of 135.41 ± 49.30 nm, a zeta potential of -29.9 ± 1.4 mV, crystalline structure, and minimal aggregation. AgNPs showed significant antibacterial activity, particularly at >20 µg/well, with the zones of inhibition varying by bacterial strain. In vitro studies demonstrated anti-inflammatory, antidiabetic (α-glucosidase and α-amylase inhibition), and antioxidant activities, with AgNPs outper

SUBMITTER: Kurra H 

PROVIDER: S-EPMC11901631 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature