Evaluating the Components, Nutrients, and Antioxidant and Anti-Inflammatory Properties of <i>Centranthera grandiflora</i> Benth Extracts.

ABSTRACT:

Background

Centranthera grandiflora Benth is commonly utilized in China to take advantage of its purported health benefits.

Methods

Here, the chemical composition, nutritional value, and bioactivity of C. grandiflora Benth extract (CGE) are characterized, and the mechanisms through which it functions were explored.

Results

CGE was found to exhibit a favorable nutritional and biosafety profile, especially due to its high amino acid and mineral contents. A UPLC-ESI-Q-TOF/MS approach identified 20 compounds. Through network pharmacology analyses, the antioxidant activity of CGE was found to be mediated through the PI3K/Akt pathway, with molecular docking results providing support for mussaenoside and azafrin as important bioactive compounds. At the cellular

SUBMITTER: Yuan W 

PROVIDER: S-EPMC11901887 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature