Psychobiotics Ameliorate Depression and Anxiety Status in Surgical Oncology Patients: Results from the <i>ProDeCa</i> Study.

ABSTRACT: Background: Psychological disorders are prevalent in patients having undergone gastrointestinal cancer surgery, and their emotional status may further deteriorate during subsequent chemotherapy. Psychobiotics are specific probiotics that have the unique characteristics of producing neuroactive substances that are thought to act on the brain-gut axis. The aim of the present study was to evaluate the benefits of a psychobiotic formula on depression and anxiety status, as well as on perceived stress, versus a placebo in patients on a chemotherapy course following gastrointestinal surgery for cancer. Patients: The enrolled patients, allocated to the psychobiotic and placebo groups, were assessed by means of these psychometric tests: Beck's Depression Inventory and the Hamilton De

SUBMITTER: Tzikos G 

PROVIDER: S-EPMC11901992 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature