Insights into Haemophilus macrolide resistance: A comprehensive systematic review and meta-analysis.

ABSTRACT:

Background

Haemophilus spp., particularly Haemophilus influenzae, are major global pathogens causing various infections. Macrolides are crucial in treating these infections, but rising resistance to macrolides in Haemophilus spp. highlights the growing threat of antimicrobial resistance (AMR).

Objective

This study aims to assess the prevalence of macrolide resistance in Haemophilus spp, across different global regions.

Methods

A systematic literature search was conducted across PubMed, Embase, Web of Science, and Scopus databases from May 2015 to December 2023 to identify studies on macrolide resistance in Haemophilus spp. The review included English-language full-text articles that reported resistance proportions and sample sizes. Study quality was assessed using the

SUBMITTER: Ahmad I 

PROVIDER: S-EPMC11902202 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature