Updated European Association of Urology (EAU) Prognostic Factor Risk Groups Overestimate the Risk of Progression in Patients with Non-muscle-invasive Bladder Cancer Treated with Bacillus Calmette-Guerin.

ABSTRACT:

Background

The 2021 European Association of Urology (EAU) guidelines contain updated prognostic factor risk groups for non-muscle-invasive bladder cancer (NMIBC). These groups are based on the following predictors of progression: tumour stage, grade, number, and size; concomitant carcinoma in situ; and age. However, the groups were derived from datasets excluding patients treated with bacillus Calmette-Guérin (BCG).

Objective

To determine the validity of the updated EAU prognostic factor risk groups in patients with NMIBC treated with BCG.

Design, setting, and participants

We reviewed patients treated with BCG at our institution between 2000 and 2018. Patients were analysed according to the receipt of "at least induction" and "adequate" BCG (as defined by the US Food

SUBMITTER: Lobo N 

PROVIDER: S-EPMC11902298 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature