Use of tenofovir-based preexposure prophylaxis among pregnant women in South Africa.

ABSTRACT:

Objective

We developed Healthy Families-PrEP to support perinatal women to use HIV prevention strategies.

Design

Single-arm study to evaluate PrEP use among pregnant women exposed to the intervention.

Methods

We offered safer conception counselling, including TDF/FTC as PrEP with adherence support (Healthy Families-PrEP) for women planning for pregnancy in South Africa with a partner with HIV or unknown serostatus. Women completed pregnancy and HIV testing quarterly and were followed for 1 year or until pregnancy end. For those initiating PrEP, electronic pillcap data and plasma were collected. We described PrEP adherence by proportion of days with pillcap openings and proportion of women with detected (≥10ng/ml) plasma tenofovir.

Results

From November 2017 to

SUBMITTER: Matthews LT 

PROVIDER: S-EPMC11902610 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature