Peak alpha frequency is related to the degree of widespread pain, but not pain intensity or duration, among people with urologic chronic pelvic pain syndrome.

ABSTRACT:

Introduction

Effective prevention and management strategies for chronic pain remain elusive. This has prompted investigations into biomarkers to better understand the mechanisms underlying pain development and persistence. One promising marker is low peak alpha frequency (PAF), an electroencephalography (EEG) measure that has been associated with increased sensitivity during acute experimental pain. However, findings regarding the relationship between PAF and chronic pain are variable, potentially due to disparate levels of central sensitization among chronic pain populations. This is evidenced by the variable extent of widespread pain, a phenotypic marker for central sensitization, observed across individuals with chronic pain.

Objective

To explore the impact of widespread

SUBMITTER: Cavaleri R 

PROVIDER: S-EPMC11902939 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature