Racial and ethnic disparities in clinical trials for pediatric obesity.

ABSTRACT:

Objective

The objective of this study was to examine the representation of historically marginalized racial and ethnic groups in pediatric obesity clinical trials.

Methods

We performed a cross-sectional analysis of clinical trials in pediatric obesity (participants aged ≤18 years) that were registered in ClinicalTrials.gov, were completed from January 2013 to August 2023, and were conducted in the United States. We quantified disparities in trial enrollment by calculating the enrollment-prevalence disparity (EPD) for each racial and ethnic group.

Results

A total of 260 trials met eligibility criteria, of which 128 trials (49.2%) reported race and/or ethnicity data. Enrollment of White, Hispanic, and Black children roughly reflects disease burden in these populations.

SUBMITTER: Coughlin CG 

PROVIDER: S-EPMC11903186 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature