Maternal oral supplementation with <i>Saccharomyces boulardii</i> I-1079 during gestation and early lactation impacts the early growth rate and metabolic profile of newborn puppies.

ABSTRACT: Nutritional programming is a manipulation of fetal and neonatal development through maternal feeding. In humans and pigs, maternal yeast supplementation was demonstrated as a promising approach to positively to modulate newborns' health. This study aimed to investigate the effects of Saccharomyces cerevisiae var. boulardii CNCM I-1079 (SB) supplementation in pregnant and lactating bitches on the newborns' early growth rate (EGR, between birth and 2 days of life), metabolic profiles, and the association between both of them. A total of 17 female dogs and their 81 puppies were included. From day 28 of gestation until the end of the study, bitches were divided into two groups, one of which received orally 1.3 × 10⁹ colony forming units of live yeast per day. Puppies f

SUBMITTER: Bendahmane I 

PROVIDER: S-EPMC11903263 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature