The skin microbiome on healthy and inflammatory altered canine skin determined by next generation sequencing.

ABSTRACT:

Introduction

Human and animal skin is colonized by a complex microbial population. An imbalance of these microorganisms is often associated with dermatological diseases.

Methods

The aim of this work was to describe the skin bacterial microbiota composition of healthy dogs and dogs with inflammatory skin lesions. Genomic DNA was sequenced using primers that target the V4 region of the bacterial 16S rRNA gene. Superficial skin swabs were collected from eight body areas of six healthy dogs (n = 48) and directly from inflammatory altered canine skin (n = 16).

Results

The skin of healthy dogs was predominantly colonized by phylum Bacillota (34.4 ± 27.2%), followed by Actinomycetota (32.2 ± 20.3%), Pseudomonadota (16.4 ± 12.2%), and Bacteroidota (8.7 ± 11.6%).

SUBMITTER: Stempelova L 

PROVIDER: S-EPMC11903403 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature