Project description:The heterogeneity in symptomatology and phenotypic profile attributable to COVID-19 is widely unknown. For the first time, our study provides the unique advantage of obtaining samples from the Middle Eastern population, an underrepresented region in genetic studies, and explore new genotypes in this population that will yield to novel genetic association. Specifically, we studied 646 patients in the United Arab Emirates. We describe strong association signals from genes on chromosomes 2, 3, 5, 11 and 13, which carry genes that are expressed in the lung, have been associated with tumour progression, emphysema, airway obstruction, and surface tension within the lung. Identifying genetic variants associated to COVID-19 susceptibility and severity may uncover novel biological insights into disease pathogenesis and identify mechanistic targets for therapeutic and vaccine development.

2022-06-03 | GSE184150 | GEO

Transdiagnostic treatment of depression and anxiety: a meta-analysis.

Project description: Not available

| S-EPMC10600931 | biostudies-literature

Precancer and cancer-associated depression and anxiety among older adults with blood cancers in the United States.

Project description: Not available

| S-EPMC8864638 | biostudies-literature

Progression of depression and anxiety symptoms in pregnancies conceived by assisted reproductive technology in the United States.

Project description: Not available

| S-EPMC10116357 | biostudies-literature

Specificity of trait anxiety in anxiety and depression: Meta-analysis of the State-Trait Anxiety Inventory.

Project description: Not available