Trends in Proton Pump Inhibitor Use in Sweden by Sex and Age: A Drug Utilisation Study.

ABSTRACT:

Background

Proton pump inhibitors (PPIs) are among the most popular drugs worldwide. Yet, there are concerns on long-term safety and poor adherence to prescription guidelines. Off-label use in children and increasing maintenance use in older adults may be particularly worrisome.

Objectives

To assess differences in PPI use by age, sex calendar year and PPI type, and to explore potential underlying indications (ulcerogenic drugs, and indications) in Sweden.

Methods

Proton pump inhibitor drug utilisation study based on the Swedish nationwide prescribed drug (2006-2023) and patient registries (2006-2022).

Results

Proton pump inhibitors were used by 14.4% (women) and 10.5% (men) of adults; and 1.0-1.5% of children and adolescents (aged < 20 years). Proton pump inhib

SUBMITTER: Brusselaers N 

PROVIDER: S-EPMC11903566 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature