Activatable second-near-infrared-window multimodal luminogens with aggregation-induced-emission and aggregation-caused-quenching properties for step-imaging guided tumor therapy.

ABSTRACT: Traditional organic luminogens, such as aggregation-caused quenching or aggregation-induced emission luminogens, only suitable to exhibit bright luminescence in the single state (i.e., solution or aggregated state), restricting their applications in heterogeneous environments. Herein, we propose a class of luminogens, aggregation-caused quenching / aggregation-induced emission dual property multimodal luminogens, which can simultaneously balance radiative and non-radiative decay processes in both the solution and aggregation states, bridging the gap between aggregation-caused quenching and aggregation-induced emission luminogens. By manipulating the rigidity planes and twisted groups of the molecules, we successfully develop a series of dual-property multimodal dyes DPM-HD1-3 with excellen

SUBMITTER: Li W 

PROVIDER: S-EPMC11903686 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature