Electrostatic enhanced terahertz metamaterial biosensing via gold nanoparticles integrated with biomolecules.

ABSTRACT: Terahertz spectroscopy has drawn great interest for the detection and characterization of biological matter, but its limited sensitivity to biomolecules with weak changes in dielectric properties with varying concentration has hinders potential bio-sensing applications. Here, a novel terahertz sensor was developed for enhancing the ability to detect biomolecules based on two electromagnetically induced transparency (EIT) metamaterials coupled with gold nanoparticles (AuNPs) integrated with biomolecules. The electrostatic interaction between AuNPs and positively charged biomolecules generates localized field enhancement at the biomolecule-metamaterial interface, resulting in a threefold increase in sensitivity for positively charged histidine that exhibit weak dielectric property changes wi

SUBMITTER: Zhang M 

PROVIDER: S-EPMC11903864 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature