A continuous approach to explain insomnia and subjective-objective sleep discrepancy.

ABSTRACT: Understanding insomnia is crucial for improving its diagnosis and treatment. However, many subjective complaints about insomnia do not align with objective measures of sleep quality, as is the case in subjective-objective sleep discrepancy (SOSD). We address this discrepancy by measuring sleep intrusions and instability in polysomnographic recordings from a large clinical database. Using machine learning, we develop personalized models to infer hypnodensities-a continuous and probabilistic measure of sleep dynamics-, and analyze them via information theory to measure intrusions and instability in a principled way. We find that insomnia with SOSD involves sleep intrusions during intra-sleep wakefulness, while insomnia without SOSD shows wake intrusions during sleep, indicating distinct etio

SUBMITTER: Herzog R 

PROVIDER: S-EPMC11903875 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature