There is a linear negative correlation between lipoprotein(a) and non-alcoholic fatty liver disease.

ABSTRACT: This study aimed to investigate the relationship between lipoprotein(a) [Lp(a)] levels and non-alcoholic fatty liver disease (NAFLD), and to analyze its linear association and subgroup differences. This cross-sectional analysis was based on data from 2308 participants in the National Health and Nutrition Examination Survey (NHANES) III. Multivariate logistic regression models were used to assess the association between Lp(a) and NAFLD, adjusting for demographic factors, lifestyle behaviors, comorbidities, and biomarkers. Subgroup analyses were conducted based on age, sex, body mass index (BMI), diabetes, and hypertension. Restricted cubic spline (RCS) regression model was used to explore the nonlinear relationship between Lp(a) and NAFLD. Higher Lp(a) levels were significantly associated w

SUBMITTER: Li C 

PROVIDER: S-EPMC11903960 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature