The relationship between diet, plasma glucose, and cancer prevalence across vertebrates.

ABSTRACT: Birds have higher plasma glucose concentrations but lower cancer prevalence than other vertebrates. However, this inverse relationship between glucose and cancer may not hold within vertebrate groups. Given that diet affects blood sugar levels, and carnivores have higher cancer risk than herbivores, we also examined whether diet correlates with plasma glucose concentrations. We collected diet, mean plasma glucose concentration, and neoplasia data for up to 273 vertebrate species from existing databases. Across vertebrates, mean plasma glucose concentration negatively correlated with cancer prevalence, but that was mostly driven by differences in mean plasma glucose concentration and cancer prevalence between birds, mammals, and reptiles. Mean plasma glucose concentration was not correlated

SUBMITTER: Kapsetaki SE 

PROVIDER: S-EPMC11904020 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature